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NSAIDs.ppt - California State University, Los Angeles

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NSAIDs.ppt - California State University, Los Angeles

Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Use of Aspirin in Unstable Angina Use of Aspirin in Unstable Angina Aspirin Toxicity - Salicylism Headache - timmitus - dizziness – hearing impairment – dim vision Confusion and drowziness Sweating and hyperventilation Nausea, vomiting Marked ...

http://www.calstatela.edu/faculty/mchen/454L%20lectures/NSAIDs.ppt

Date added: October 29, 2011 - Views: 187

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PowerPoint Presentation

what side effects are seen with nsaids. what group of patients are at risk for toxicity from nsaids? how do you monitor pts. on nsaids?

http://www.myoops.org/cocw/mit/NR/rdonlyres/Health-Sciences-and-Technology/HST-151Principles-of-PharmacologySpring2003/0624D0B1-EBB1-493F-A3F7-87BC61D2280C/0/ln16ahms5815.ppt

Date added: January 24, 2013 - Views: 13

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Canine NSAIDs and Client Education: An FDA Perspective

Title: Canine NSAIDs and Client Education: An FDA Perspective Subject: Dog NSAIDs and adverse reaction signs to look for Author: US FDA Center for Veterinary Medicine

http://www.fda.gov/downloads/AboutFDA/Transparency/Basics/UCM292822.ppt

Date added: June 23, 2012 - Views: 43

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Nonsteroidal Antiinflammatory Drugs ( NSAIDs )

Nonsteroidal Antiinflammatory Drugs (NSAIDs) ... Drug interactions Aspirin Toxicity In adults, salicylism (tinnitus, hearing loss, vertigo) occurs as initial sign of toxicity after aspirin or salicylate overdose or poisoning.

http://elearning.najah.edu/OldData/pdfs/3456Nonsteroidal%20Antiinflammatory%20Drugs%20(NSAIDs).ppt

Date added: May 31, 2012 - Views: 101

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PowerPoint Presentation

NSAIDs Books: 1. Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry 11th ed ... they do not comply with SAR 1 possibly act by some other mechanism The first drug Acetanilide is out of market due of toxicity (both blood and liver disorders Phenacetin ...

http://faculty.swosu.edu/faruk.khan/share/MedChem1/PHARM4515-16%20(NSAIDs).ppt

Date added: April 1, 2013 - Views: 84

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pfizer capsule study - Food and Drug Administration

Small Bowel Toxicity of Nonselective NSAIDs Revealed by Capsule Endoscopy: Results From a Pivotal Clinical Trial Glenn M. Eisen, M.D., M.P.H. Associate Professor of Medicine

http://www.fda.gov/ohrms/dockets/ac/05/slides/2005-4090OPH1_08_Eisner.ppt

Date added: October 29, 2011 - Views: 12

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PowerPoint Presentation

... immune system Innate immune system Perceived threat Infection 1 2 Anti-inflammatory & Immunosuppressant Drugs 1 NSAIDS Acetaminophen Antihistamines ... Drugs Inhibitors of Eicosanoid Production Notable NSAIDS NSAID Therapeutic Effects NSAID & Acetaminophen Toxicity Acetaminophen ...

http://physio.ucsf.edu/GEMS/courses/Immunology/materials/fa11_essential_immunology/september_2/anti_inflamimmunsupp1_masters.ppt

Date added: February 27, 2012 - Views: 51

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Canine NSAIDs and Client Education - Clinical Pharmacology ...

NSAIDs: Signs of Toxicity As a class, NSAIDs are associated with gastrointestinal, renal and hepatic toxicity. The four most commonly reported adverse events are vomiting, anorexia, depression, and diarrhea. Others include: gastric ulceration, ...

http://cpharm.vetmed.vt.edu/FDA/Canine%20NSAIDs%20and%20Client%20Education.ppt

Date added: August 17, 2011 - Views: 73

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THE INFLAMMATORY RESPONSE - Dalhousie University

NSAIDs (non steroidal anti-inflammatory drugs) Biol 4407/Bioc 4806.5/ Nesc 4376/PHC 5409B Dr.T.C. Peterson Mechanism of action of Allopurinol Allopurinol inhibits synthesis of uric acid by competing for the enzyme xanthine oxidase.

http://pharmacology.medicine.dal.ca/undergraduate/NSAIDS.ppt

Date added: September 15, 2011 - Views: 147

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PowerPoint Presentation

Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Common therapeutic indications Common adverse effects Different pharmacokinetics and potency Different chemical families

http://www.philadelphia.edu.jo/academics/htwaij/uploads/NSAIDs.ppt

Date added: February 10, 2013 - Views: 43

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NSAIDS and Tylenol

NSAIDS & Tylenol Jane E. Smith, MHSA, RN, C, ONC Objectives Review the pathophysiology of the inflammatory response Discuss the mechanism of action for non-steroidal anti-inflammatory drugs and Tylenol Discuss the indications, side effects, and nursing implications related to NSAIDS and Tylenol ...

http://www.ravenwood-pa.com/npceu/content/courses/all/ppt/7724/nsaids%20and%20tylenol-smith.ppt

Date added: June 7, 2013 - Views: 4

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PowerPoint Presentation

Title: PowerPoint Presentation Author: Susan Masters Last modified by: Susan Masters Created Date: 9/3/2007 9:52:46 PM Document presentation format

http://physio.ucsf.edu/GEMS/courses/Immunology/materials/fa11_essential_immunology/september_2/anti_inflamimmunsupp2_masters.ppt

Date added: December 9, 2011 - Views: 56

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PowerPoint Presentation

Inhibition of COX-1 is responsible for their GIT toxicity. Most currently used NSAIDs are somewhat selective for COX-1, but selective COX-2 inhibitors are available. Analgesic Antipyretic Anticoagulant Anti-inflammatory (at higher doses) Non -steroidal Anti-Inflammatory Drugs Feature Narcotic ...

http://judoctor2011.files.wordpress.com/2013/02/nsaid-1.ppt

Date added: May 9, 2013 - Views: 13

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nsaid.ppt - Southern Illinois University School of Medicine

... ADME/Side Effects of NSAIDs The T1/2 of the different NSAIDs vary from short, less than 1 hr., to longer than 12 ... Virtually all NSAIDs can cause dyspepsia and GI toxicity including ulceration. All except the nonacetylated ... nsaid.ppt Author: Donald M. Caspary Last modified ...

http://www.siumed.edu/oec/Year2/artheritis-longPPT.ppt

Date added: December 18, 2012 - Views: 29

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NSAIDs and COX-2- Selective Inhibitors

Title: NSAIDs and COX-2-Selective Inhibitors Author: 정준영 Last modified by: 정준영 Created Date: 1/3/2001 5:49:08 AM Document presentation format

http://www.anesthesia21.com/data/2006/pain/ch16NSAIDs%20and%20COX-2-Selective%20Inhibitors.ppt

Date added: May 2, 2013 - Views: 9

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Non-steroidal anti-inflammatory drugs - Download Center

Dysmenorrhea ADVERSE EFFECTS SHARED BY N-NSAIDS GIT upsets ( nausea, vomiting) ... Therapeutic doses elevate liver enzymes Large doses cause liver & kidney necrosis Treatment Of toxicity of paracetamol by : N- acetylcysteine ( SH ...

http://www.ksums.net/files/Archive/1st/432/02%20MUSCULOSKELETAL%20BLOCK/Female/Pharmacology/Lecture%201-%20NSAIDs.ppt

Date added: December 18, 2013 - Views: 10

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PowerPoint Presentation

... asthma Nonsteroidal Antiinflammatory Drugs (NSAIDs) Nonsteroidal Antiinflammatory Drugs (NSAIDs) Inflammation is ... Special Considerations Aspirin sensitive patients may develop anaphylactic reactions angioedema asthma Chronic toxicity is the same as for aspirin tinnitus ...

http://people.emich.edu/smcgregor/Pharmacology/Lectures%202k4/11-28-04%20Anti-inflammatory.ppt

Date added: November 7, 2012 - Views: 39

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Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) - The SC EBS

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) NSAIDs - Effects Anti-inflammatroy - inhibit synthesis of prostaglandins by blocking the cyclooxygenase (COX) enzyme Types COX –1 – found in stomach COX –2 – found at injury site Anti-inflammatory Effects Inhibits chemical mediator ...

http://www.ebsummit.info/SportsMedicineGuide/NSAIDS.PPT

Date added: January 7, 2013 - Views: 64

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THE INFLAMMATORY RESPONSE - بذرة خير

... toxicity Kidney failure Congestive heart failure Cox-2 inhibitors GI problems May delay ulcer healing Increased risk of CV disease Kidney ... but also have been shown to increase bleed time by 3-4 minutes. NSAIDs have always been associated with increased GI bleed and now are associated ...

http://ksupc.com/download/xArchive/level9/427/Medicinal%20chemistry/Dr.%20Wafa'a/NSAIDs.ppt

Date added: May 2, 2013 - Views: 17

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Drug-induced Kidney Disease - دانشگاه علوم ...

Title: Drug-induced Kidney Disease Author: Dr.N.Ahangar Last modified by: drNAhangar Created Date: 7/14/2010 1:16:54 PM Document presentation format

http://www.bums.ac.ir/shares/drugfood/drugfood/tosee/seminar/new/Drug-induced%20Kidney%20Disease.ppt

Date added: February 5, 2013 - Views: 46

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NSAIDs

Non-Steroidal Anti-Inflammatory Drugs ibuprofen Meghin Gjerswold 12.01.2006 UWSOP at Genelex

http://www.philadelphia.edu.jo/academics/ybatineh/uploads/ph20.ppt

Date added: April 1, 2014 - Views: 7

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PowerPoint Presentation

Inhibition of COX-1 is responsible for their GIT toxicity. Most currently used NSAIDs are somewhat selective for COX-1, but selective COX-2 inhibitors are available. Analgesic pain. Antipyretic Anticoagulant platelet aggregation . Anti ...

http://judoctor2011.files.wordpress.com/2013/02/nsaid-11.ppt

Date added: May 3, 2013 - Views: 5

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PowerPoint Presentation

Antiinflammatory Agents and Nonsteroidal Antiinflammatory Drugs (NSAIDs) NSAIDs Large and chemically diverse group of drugs with the following properties: Analgesic Antiinflammatory Antipyretic NSAIDs: Mechanism of Action Activation of the arachidonic acid pathway causes: pain headache fever ...

http://intranet.tdmu.edu.ua/data/kafedra/meds/eng/ADN%20Program/Freshman%20year/Spring%20semester/Pharmacology/Anti-inflammatory,%20Antirheumatoid%20and%20Related%20Agents.ppt

Date added: November 21, 2013 - Views: 12

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Salicylates - University of Utah

NSAIDS, DMARDS, BRMs and Drug Therapy of Arthritis Drug Therapy of Gout Garold S. Yost, Ph.D. ... bound to plasma proteins All cause GI ulceration or bleeding and renal toxicity Misoprostol (Cytotec) used to prevent or treat GI injury Omeprazole ...

http://umed.med.utah.edu/ms2008/Vault/MuscSkel/20051117-1-NSAIDSArthritisAndGout2005.ppt

Date added: September 17, 2011 - Views: 31

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Lecture 6 - Harper College Palatine IL 60067 | Begin a Degree ...

- NSAIDS (antiinflammatory & muscle relaxants) Analgesics Nonnarcotics Aspirin, Acetaminophen, Ibuprofen & Naproxen - Not addictive & less potent than ... OD = Toxic to hepatic cells = liver toxicity Analgesics Narcotics Used for moderate to severe pain - IV, IM, PO, supp, epidural ...

http://harpercollege.edu/ls-hs/nur/120/sdolezal/lesson6_files/lesson6.ppt

Date added: August 8, 2014 - Views: 3

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NSAIDs in the ED: Focus on ibuprofen and Ketorolac

NSAIDs in the ED: Focus on Ibuprofen & Ketorolac Andrea Wilson ... Individual NSAIDs Big differences in toxicity Acetaminophen and Ibuprofen lower risk for UGIB. Ketorolac more toxic Relative Risk for UGIB by individual NSAID (prescription dosing) Why are there relative toxicities?

http://calgaryem.com/files/newest_nsaids.ppt

Date added: December 17, 2012 - Views: 63

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Drug Interactions - Pharmaceutical Society of New Zealand

... drug causes a change in patient response to another drug without altering that drug’s pharmacokinetics Eg increase toxicity of digoxin caused by diuretic induced ... CYP2D6 Time course of interaction ... flow Methotrexate and NSAIDs NSAIDS can decrease ...

http://www.psnz.org.nz/public/cop/college_information/affiliated/nzcp/drug%20interactions%20course/druginteractions.ppt

Date added: October 26, 2011 - Views: 119

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BIOCHEMICAL MECHANISMS OF DRUG TOXICITIES

TOXICITIES PRODUCED BY DRUGS Hepatic Skin Renal Pulmonary Cardiac Neurological Lupus Anaphylaxis ... 15 patients resulted in 7 developing severe mitochondrial liver damage with 5 dying and 2 receiving liver transplants Toxicity was not ... REACTIONS WITH NSAIDS ...

http://cc.nih.gov/researchers/training/principles/ppt/biochemical_mechanisms_of_drug_toxicity_2006-2007.ppt

Date added: August 19, 2013 - Views: 8

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عرض تقديمي من PowerPoint

Other NSAIDs B) Selective COX2 inhibitors (COXIBS): Meloxicam, Celecoxib , Etoricoxib: Used mainly as analgesic, ... (free radical) which is hepatotoxic Used where aspirin is C.I as analgesic or antipyretic. Toxicity: Large dose>15g cause fatal acute hepatotoxicity (hepatic necrosis) ...

http://freshmendentists.files.wordpress.com/2013/05/other-nsaids.ppt

Date added: October 21, 2014 - Views: 1

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PowerPoint Presentation

Potential for Toxicity. Identify Target Organs for Toxicity. Characterize . Dose Dependence. Relationship to Exposure. Potential Reversibility. ... Effective chemopreventive agents included NSADS/modified NSAIDS, p53 modulators, retinoids and budesonide.

http://deainfo.nci.nih.gov/advisory/bsa/bsa1110/presentations/1315Steele.pptx

Date added: May 2, 2013 - Views: 17

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ANTI-INFLAMMATORY AGENTS

anti-inflammatory agents adapted from materials originally prepared by and used with permission of ray colucci, rn msn

http://studentnurse.yolasite.com/resources/NCM101/pharmacology/ANTIINFLAMMATORY.ppt

Date added: August 24, 2014 - Views: 1

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Arthritis Medications Part I - St. Joseph's Hospital

Dr. Sherry Rohekar May 13, 2010 ... Cochrane Library 2006. Compared to NSAID - Pain Compared to NSAID - Toxicity Recent RCT published in NEJM that examined 1583 patients ... Nonprostaglandin-mediated NSAIDs insert into biological membranes and disrupt cell functions Nonsteroidal ...

http://www.sjhc.london.on.ca/sites/default/files/npfp/arth_meds_1.ppt

Date added: August 5, 2013 - Views: 11

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NSAIDS: Reducing the risk - pennine-gp-training.co.uk

Noticed many patients had NSAIDs on repeat rx without gastroprotection Confused about when/whom to give PPI cover to Felt like I was prescribing it by the bucketload ... 47:458–463 Management of NSAID-Induced Gastrointestinal Toxicity: Focus on Proton Pump Inhibitors.

http://www.pennine-gp-training.co.uk/audit-nsaids-and-ppi-2011.ppt

Date added: November 30, 2011 - Views: 19

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Chapter 19 Drugs: Chemical Cures, Comforts, and Cautions

Chapter 14 Drugs: Chemical Cures, Comforts, and Cautions Drug Chemical substance that affects the functioning of living things May treat, diagnose, and prevent disease Dates to ancient times Over 9900 drugs available in U.S. Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Most widely used ...

http://andromeda.rutgers.edu/~jimms/drugs.ppt

Date added: September 4, 2011 - Views: 79

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PowerPoint Presentation

Drug Toxicity I Toxicology: Molecular Mechanisms ... Largely due to drugs that alter blood flow : NSAIDs (eg. aspirin) reduce prostaglandins which in turn reduces blood flow/GFR ACE inhibitors (eg. ramipril) increase blood flow/GFR (ii) allergic nephritis allergic reaction to NSAIDs ...

http://www.reading.ac.uk/web/FILES/pharmacy/PM2PB4Toxicologylecture2011.ppt

Date added: December 17, 2012 - Views: 42

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Rheumatoid Arthritis - Iowa Health Des Moines Medical ...

Rheumatoid Arthritis A symmetric, peripheral polyarthritis of unknown etiology that, untreated or if unresponsive to therapy, typically, ... NSAIDS Toxicity increases with dose escalation regardless of agent Gastroprotection in patients with risk factors for gastropathy ...

http://www.ihsmeded.org/documents/InternalMedicine/Rheumatoid%20Arthritis.ppt

Date added: July 12, 2013 - Views: 18

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عرض تقديمي من PowerPoint

Non Steroidal Anti-Inflammatory Drugs (NSAIDs) Classification Heterogeneous compounds and can be ... The syndrome may be due to mitochondrial damage. Non Steroidal Anti-Inflammatory Drugs (NSAIDs) Aspirin Toxicity (10-30g) Characterized by: 1) hyperventilation leading to respiratory ...

http://freshmendentists.files.wordpress.com/2013/05/nsaids.ppt

Date added: October 21, 2014 - Views: 1

ppt
PowerPoint Presentation

Antihypertensive Agents General Nursing Implications Instruct patients to change positions slowly Hot ... Teach patient to eat high K foods Cross allergies may exist to sulfonamides Concurrent digoxin Rx may lead to digoxin toxicity NSAIDS may decrease diuretic effect Concurrent ...

http://www2.sunysuffolk.edu/burgerk/nursing/NUR133%20Spring%2009/PPP%20for%20Webpage/Web%20Circulatory%20Antihypertensive%20Meds.ppt

Date added: December 27, 2012 - Views: 20

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PowerPoint Presentation

... (Calne) 1982 50% 1 year survival (Calne) 1988 Living Related Liver transplant (Raia) 1994 Living donor R lobe ... NSAIDs, Valproate, carbamazepine ... Bacterial/Viral/Fungal Drug toxicity Renal Impairment Acute cellular rejection Acute cellular Rejection ...

http://www.adhb.govt.nz/CETU/images/FRACP%20presentations/David%20Orr%20LT%20talk.ppt

Date added: May 11, 2012 - Views: 42

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PowerPoint Presentation

... Trovafloxacin is Toxic at Therapeutic Concentrations ACTIVTox displays fine structural discrimination among NSAIDS Inhibition of cyps Alters Toxicity of Celecoxib Rofecoxib Is Not Metabolized Rofecoxib does not activate Apoptosis Only sulindac induces cyp1A Three Compounds have ...

http://www.toxicology.org/isot/rc/ncac/symposia_files/Spring2004Kelly.pps

Date added: July 19, 2012 - Views: 19

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Pain Assessment & Management - University of Chicago

Pain Assessment & Management ... Reprinted with permission. Non-opioid medications Acetominophen 650mg tid-qid : concern for hepatic toxicity >3-4grams NSAIDs ... due to side effects and unclear efficacy compared to other products Adjuvants Non-pharmacologic Topicals Tylenol NSAIDS, ...

http://champ.bsd.uchicago.edu/painControl/documents/FINALLimayePainAssessmentManagement.ppt

Date added: September 8, 2011 - Views: 71

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No Slide Title

... Treadmill with minimal or no elevation Nonopioid Analgesic Therapy First-line—Acetaminophen Pain relief comparable to NSAIDs, less toxicity Beware of toxicity from use of multiple acetaminophen-containing products Maximum safe dose = 4 grams/day Nonopioid Analgesic Therapy ...

http://www.rheumatology.org/education/resources/hir/4_oa.ppt/

Date added: August 9, 2014 - Views: 1

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PowerPoint Presentation

The best direct evidence that NSAIDs inhibit the process of carcinogenesis in humans comes from several studies in patients with FAP ... the efficacy of sulindac in FAP patients has been associated with low toxicity. Although heterogenous results have been seen, many studies have ...

http://swog.org/Visitors/S0820/Slides.ppt

Date added: May 10, 2013 - Views: 23

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PowerPoint Presentation

Rheumatoid Arthritis Carole Callaghan Principal Pharmacist NHS Lothian

http://www.nes.scot.nhs.uk/media/347489/core_course_lecture_-_ra_2010.ppt

Date added: July 7, 2013 - Views: 2

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Non-steroidal anti-inflammatory drugs

NON-STEROIDAL ANTI-INFLAMMATORY DRUGS * * ADVERSE EFFECTS Adverse effects shared by NS-NSAIDs (Gastric upset less frequent than aspirin) Rare hematologic effects (agranulocytosis & aplastic anemia ).

http://www.ksums.net/files/Archive/3rd/428/Pharmacology/Female/1st%20Term/Tutorial%20NSAIDs%20-%20Copy.ppt

Date added: May 10, 2012 - Views: 25

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PowerPoint Presentation

... Anti-inflammatory, vasodilator, anti-pyretic ... 50-200 mg/day tincture 5-20 drops Chemistry, Functions, Toxicity Sesquiterpene lactons: parthenolide, (and derivatives) canin, balchanin, volatile oils ... (NSAIDs) Gingko Gotu Kola Indications: St. John’s Wort Actions ...

http://web.campbell.edu/faculty/nemecz/Herbclass/lectures/CNS%20herbs.ppt

Date added: May 11, 2012 - Views: 60

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Lithium Toxicity - Calgary Em

Title: Lithium Toxicity Author: Owner Last modified by: Owner Created Date: 8/8/2006 8:48:48 PM Document presentation format: On-screen Show Other titles

http://calgaryem.com/files/2006_08_10-Sacks_Lithium_Toxicity-LXE.ppt

Date added: February 2, 2013 - Views: 18

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Aspirin and Antiinflammatory Agents - Arkansas State University

... excr’d unchanged (25%) Rate excr’n incr’d in alkaline urine Irreversible inhibitor of COX enz’s Toxicity may be local or ... Presentation Actions of Leukotrienes PowerPoint Presentation Drugs Inhibiting Prostanoid Prod’n Commonly Used NSAIDs PowerPoint ...

http://www.clt.astate.edu/agrippo/s06lect6Aspirin.ppt

Date added: October 30, 2011 - Views: 82

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Non Steroidal Anti Inflammatory Drugs - به سامانه ...

Non Steroidal Anti Inflammatory Drugs, Nonopioid Analgesics By S.Bohlooli, PhD The immune reponse May lead to Cure More injury Eicosanoids Kinins Neuroptides Histamine Cytokines Free radicals Therapeutic strategies Relief of Pain Slowing or arresting the tissue damaging process Drugs NSAIDs ...

http://eprints.arums.ac.ir/3664/2/Anti%20Inflammatory%20Drugs.ppt

Date added: December 9, 2013 - Views: 3

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Anti-inflammatory Medications - Florida International University

Chapter 3 Anti-inflammatory Medications NSAIDs The use of NSAIDs for the treatment of sports-related injuries, as well as other maladies, (namely osteoarthritis) continues to rise.

http://www2.fiu.edu/~dohertyj/Pharmacology%20Chapter%203.ppt

Date added: January 29, 2012 - Views: 69