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Bilirubin - University of Massachusetts Lowell

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Bilirubin - University of Massachusetts Lowell

Bilirubin. The yellow breakdown product of normal heme catabolism. The principle pigment in bile. Bilirubin circulates in the bloodstream in two forms:

Date added: December 3, 2014 - Views: 1

Hyperbilirubinemia - Stanford University

Outcomes in a Population of Healthy Term and Near-Term Infants With Serum Bilirubin Levels of >19 mg/dL Who Were Born in ... No cases of kernicterus at bili ...

Date added: October 18, 2013 - Views: 12

PowerPoint Presentation

... mental retardation known as kernicterus If bilirubin levels are ... unconjugated” bilirubin NORMAL BILIRUBIN METABOLISM Uptake of ...

Date added: October 25, 2011 - Views: 173

MLAB 2401: Clinical Chemistry Keri Brophy-Martinez

... Onset seen at bilirubin levels > 3.0 mg/dL Kernicterus Yellow staining of the meninges of the brain due to bilirubin Found in newborns Causes brain ...

Date added: May 18, 2013 - Views: 12

PowerPoint Presentation

... Due to immaturity of the enzymes involved in bilirubin conjugation High levels of unconjugated bilirubin ... known as kernicterus If bilirubin levels ...

Date added: October 29, 2011 - Views: 39

The Normal Newborn, Assessment, Care, Feeding

The Normal Newborn : Assessment, Care ... Increased Bilirubin Levels Jaundice in the 1st day is NOT ... Hepatic Function Increased Bilirubin Levels Kernicterus ...

Date added: October 2, 2011 - Views: 495

Jaundice Noted in the First 24 Hours After Birth...

Overview Introduction Jaundice in newborns and kernicterus Infant safety seats on ... permanent brain damage from very high bilirubin levels Jaundice ...

Date added: September 12, 2011 - Views: 83

Obstructive Jaundice - Wikispaces

This hyperbilirubinemia subsequently causes increased levels of bilirubin in the ... due to deposition of bilirubin,a condition known as kernicterus leading to ...

Date added: March 30, 2014 - Views: 22

PowerPoint Presentation

Kernicterus in newborns Bilirubin Metabolism: ... Serum levels of iron, transferrin, and ferritin (for hemochromatosis) Serum levels of ceruloplasmin ...

Date added: May 30, 2012 - Views: 81

Evidence-Based Medicine for AAP Leadership

First use of phototherapy History 1970s Bilirubin toxicity at lower levels? ... Kernicterus rare if Total Serum Bilirubin (TSB) kept < 20 mg/dl RCT: ...

Date added: November 6, 2011 - Views: 58

Neonatal jaundice education presentation -...

Raised levels of bilirubin in the blood. ... Neonatal jaundice. Acute bilirubin encephalopathy. ... Kernicterus. Pathological term.

Date added: June 22, 2013 - Views: 22

Blood Cells and Vessels - Dr Magrann

Red Blood Cell Breakdown. Hemoglobin in RBC’s is broken down to bilirubin. Bilirubin is excreted in bile and urine, and elevated levels may indicate certain diseases.

Date added: February 7, 2014 - Views: 25

Respiratory Therapy Licensure Alabama

Decreased clearance of bilirubin from the plasma due to decrease levels of ligandin and uridine ... Most serious complication is kernicterus (bilirubin pigment ...

Date added: August 16, 2013 - Views: 4

What is there to Know About a Yellow Baby?

We no longer see the high bilirubin levels that necessitate double volume exchange transfusion. History. Kernicterus. Why do we Worry? Unconjugated bilirubin ...

Date added: November 4, 2013 - Views: 11

BLOOD - Wilkes-Barre Area Career & Technical...

Baby becomes jaundice; rises plasma levels of bilirubin: hyperbilirubinemia; kernicterus; staining of the brain with bilirubin; severe MR.

Date added: August 31, 2013 - Views: 40

Bilirubin Metabolism - Wikispaces

Bilirubin Metabolism in the Liver. Uptake of Bilirubin by hepatocytes: Bilirubin dissociates from its carrier albumin & enters hepatocytes. Conjugation

Date added: September 18, 2013 - Views: 10

Degradation of heme - KSU

Formation of bilirubin. The first step in the degradation of heme is catalyzed by the microsomalhemeoxygenase system of the reticuloendothelial cells.

Date added: June 28, 2012 - Views: 3

Introduction to Quality Improvement in Children’s...

kernicterus. in 1875 in Berlin . In 1904, Christian Georg Schmorl was the first to use the term . kernicterus (nuclear jaundice) ... Bilirubin Metabolism in the Newborn.

Date added: January 27, 2012 - Views: 29

Neonatal Anesthesia - Ain Shams University

Neonatal Anesthesia ... low serum protein levels are liable to get Kernicterus (bilirubin encephalopathy) due to increased levels of unconjugated serum bilirubin.

Date added: May 13, 2013 - Views: 26

Neonatal Jaundice

Warning There are no bilirubin levels which are known to be safe or which will definitely cause kernicterus.

Date added: September 24, 2013 - Views: 3

P020A - Porterville College

Course Objective #30. Identify the causative agent and the effects on the fetus in the following maternal infections: Rubella. Toxoplasmosis. Syphilis

Date added: March 1, 2014 - Views: 19

PowerPoint Presentation

... 33% BILI GLUCURONIDES Recessively Inherited Absence of Bilirubin-UGT Unconjugated Hyperbilirubinemia Kernicterus BILIRUBIN 30 mg ... Bilirubin levels in ...

Date added: December 23, 2014 - Views: 1

PowerPoint Presentation

Kernicterus (bilirubin encephalopathy) can result from untreated hypergbilirubinemia with bilirubin levels at or higher than 20 mg/dl → mental retardation.

Date added: March 21, 2013 - Views: 114

Rh blood system

... bilirubin in the neuronal cells--- Kernicterus Injecting Anti D ... to minimize the levels of bilirubin 1 ... Rh blood system Author: Dr Anjum ...

Date added: December 22, 2013 - Views: 7


... writhing movements) cerebral palsy—kernicterus (elevated bilirubin levels ... Alcohol and socialization Loss of inhibitions with .05 blood alcohol levels ...

Date added: November 23, 2013 - Views: 30

PowerPoint Presentation

Elevated blood levels of aminotransferases indicate damage to cells rich in these enzymes (as disease to tissue or physical trauma )

Date added: August 24, 2014 - Views: 2

Anesthesia and Liver Disease

Anesthesia and Liver Disease E.A. Steele, MD ... Bilirubin exrection heme ... obstruction kernicterus Total Albumin Low levels Decreased production Liver disease, ...

Date added: May 2, 2013 - Views: 2

Slide 1

Bilirubin is a Neurotoxin Who is ... But kernicterus, ... A small percentage of babies with jaundice have dangerously elevated levels of a naturally occurring ...

Date added: May 24, 2013 - Views: 5

Blood bank/transfusion medicine lab - Indiana...

Normal Hemoglobin levels . Men: 13.8 ... and diffuse into the brain causing kernicterus and acute bilirubin encephalopathy. ... Blood bank/transfusion medicine lab ...

Date added: November 22, 2014 - Views: 11

Porfyriny a žlučová barviva - Univerzita Karlova v...

Hyperbilirubinemia. Elevated bilirubin levels in the blood (>10 mg/l); bilirubin may diffuse into peripheral tissues, giving them a yellow color (jaundice)

Date added: April 3, 2015 - Views: 1

Slide 1

Epidemiology . HCC is the fifth most common cancer and the third most frequent cause of cancer death worldwide, with an estimated 560,000 new cases per year.

Date added: May 27, 2014 - Views: 8

Human Albumin: Physiology, Pathophysiology and...

High levels of bilirubin are of particular concern among neonates and infants, ... (kernicterus). High levels of bilirubin occur in infants because the liver, ...

Date added: March 6, 2015 - Views: 1

Pediatric Nursing Unit Eight - Majmaah University

Hyperbilirubinemia is defined as excessive levels of bilirubin in ... Loss of moro or startle reflex can indicate possible brain damage due to Kernicterus. Neonatal ...

Date added: October 6, 2013 - Views: 23

Fetal Haemolytic Disease - School of Medicine

Fetal Haemolytic Disease ... Increased bilirubin Jaundice postnatally Kernicterus Prevention Anti-D after any ... Serial measurements of Anti-D levels.

Date added: May 13, 2013 - Views: 2

Penicillins and Cephalosporins - The University of...

(at therapeutically attainable levels) ... Neutropenia Kernicterus in neonates Dicloxicillin Oral NOT equivalent to IV Ox ... Penicillins and Cephalosporins Author:

Date added: September 29, 2014 - Views: 13

Blood and Blood Component Therapy - Indiana...

Without therapy unconjugated/indirect bilirubin can reach toxic levels ... Kernicterus and Acute Bilirubin Encephalopathy . ... Blood and Blood Component Therapy

Date added: October 24, 2013 - Views: 17

General Pharmacology

Sulfonamides when administered to a neonates can displace bilirubin from binding sites and can cause kernicterus. ... bilirubin levels are generally below 345 ...

Date added: May 27, 2015 - Views: 1

Seminar On Altered kinetics in pediatrics


Date added: April 9, 2014 - Views: 1

Age and Pharmacokinetics Pediatric and Geriatric...

Age and Pharmacokinetics ... Most important in displacement of bilirubin from albumin resulting in toxicity (kernicterus) ...

Date added: October 22, 2011 - Views: 125

Management of Common Breastfeeding Problems

Management of CommonBreastfeeding Problems. Breastfeeding Residency Curriculum. Prepared by. Andrew Hsi MD, MPH. and. Larry Leeman MD, MPH. University of New Mexico ...

Date added: December 3, 2014 - Views: 2

High Risk Neonates - Austin Community College

Bilirubin levels should NOT exceed 5 mg/dl. Coombs Test. ... Kernicterus – Deposits of conjugated and unconjugated bilirubin in the basal ganglia of the brain.

Date added: August 15, 2013 - Views: 60

PowerPoint Presentation

... conditions leading to abnormal levels. ... Complications: anemia; hyperbilirubinemia; kernicterus. Excess unconjugated bilirubin from red cell breakdown.

Date added: March 6, 2012 - Views: 56

Cerebral Palsy: The Stigma, The Fears and the...

Kernicterus (excessively high bilirubin/jaundice) Infections (Intrauterine and ... Governments at all levels must respond to the cry of these children and their ...

Date added: March 28, 2014 - Views: 6

Sedatives, Hypnotics & Anxiolytics -

No more used as sedative hypnotics but are applied as general anesthetics ... Neonatal jaundice and kernicterus. Enzyme induction causes metabolism of bilirubin, ...

Date added: April 27, 2014 - Views: 3

1 -

What are the conducting fibers that rapidly spread the electrical signal throughout the ventricles? a. ... Kernicterus. 76. ... b. increase plasma K+ levels.

Date added: September 10, 2013 - Views: 13


Kernicterus Developmental Pediatrics Louis Meng, PL2 November 12th 2002 History Earliest work on jaundice from Baumes-1785, and Hervieux-1847 Kernicterus was first ...

Date added: October 25, 2011 - Views: 63

Common neonatal problems - OMC Forum • Index page

The neonatal period ... They are also more likely to develop kernicterus, ... High levels bilirubin may require phototherapy or exchange transfusion in rare severe ...

Date added: August 1, 2013 - Views: 50

Jaundice and Kernicterus in the Newborn - United...

Jaundice and Kernicterus in the Newborn B. Paul Choate, M.D. Fort Carson MEDDAC Introduction Neonatal jaundice affects 60% of term babies and 80% of pre-term babies ...

Date added: October 23, 2014 - Views: 6

الشريحة 1

- serum iron levels. Treatment. ... - Kernicterus: is a form of brain ... - The fetus is observed by serial amniocentesis to determine bilirubin level.

Date added: August 21, 2013 - Views: 6