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Aptamer Structure Medicinal Chemistry Process Considerations in Safety Assessment of Aptamers Discovery Toxicology In vitro Complement Activation In vitro ...

http://www.massbio.org/writable/committees/presentations/mbc_21feb2008.ppt

Date added: October 30, 2011 - Views: 111

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Overview of your immune system - Information Management ...

... 657 RNA aptamers -- antibody-like properties Vitamin b12-binding RNA aptamer Slide 10 Let the immune system make enzymes for you Wedemayer et al. ...

http://www.its.caltech.edu/~bi1/archives/files_2011/lectures/lecture26/lecture26.ppt

Date added: January 29, 2013 - Views: 20

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Flavin mononucleotide RFN aptamer Genetic Control Mechanisms Tom Cech, Nature (2004) 428: 263-264. Genetic Control Mechanisms - RIBOSWITCHES Tom Cech, Nature ...

http://chemistry.creighton.edu/~jksoukup/lecRiboswitches2008.ppt

Date added: October 31, 2011 - Views: 61

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Label-Free Protein Biosensor Based on Aptamer-Modified Carbon ...

Label-Free Protein Biosensor Based on Aptamer-Modified Carbon Nanotube Field-Effect Transistors Kenzo Maehashi, Taiji Katsura, Kagan Kerman, Yuzuru Takamura,

http://light.eecs.berkeley.edu/courses/ee235_sp07/student_presentations/0305/(4)%2003052007_Ryan_EE235.ppt

Date added: November 30, 2012 - Views: 15

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Impact Aptamer recognition elements enable detection of nucleic acids, proteins, small molecules, ... PowerPoint Presentation Last modified by: robert.kokoska

http://www.strategicstudiesinstitute.army.mil/pdffiles/strat20/panel-1-kokoska/kokoska.ppt

Date added: October 12, 2011 - Views: 55

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Reprogramming Cellular Behavior with RNA Controllers Responsive to Endogenous Proteins Stephanie J. Culler, Kevin G. Hoff, Christina D. Smolke

http://openwetware.org/images/4/44/Tinaandrew20.385.ppt

Date added: May 6, 2013 - Views: 10

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DNA-based cell targeting - OpenWetWare - Main Page - OpenWetWare

Bad: If we can control amount of aptamer bound to cell surface, probably can get as much/ better control by delivering protein bound directly to the aptamer.

http://openwetware.org/images/d/d2/Targeting.ppt

Date added: March 31, 2012 - Views: 10

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Factor IX a Inhibition Aptamer Technology Overview and First ...

Factor IXa Inhibition Aptamer Technology Overview and First Results with RB006/RB007 Mauricio G. Cohen, MD Associate Professor of Medicine Director, Cardiac Cath Lab

http://www.clinicaltrialresults.org/Slides/Factor%209%20inhibition%20via%20aptamer.ppt

Date added: November 8, 2011 - Views: 37

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Folie 1 - FLI - Leibniz Institute for Age Research

The Aptamer Database is a comprehensive, annotated repository for information about aptamers and in vitro selection. This resource is provided to collect, ...

http://www.imb-jena.de/www_bioc/3D/3D_LECTURE_2005_2.ppt

Date added: June 11, 2013 - Views: 5

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Supplementary Figure 1 A B 7.93 PEG-Aptamer 500 400 9.66 NH2-Aptamer 300 200 Absorbance (mAU) 100 7.93 PEG-Aptamer 300 250 200 150 100 50 5.0 10.0 15.0 20.0 25.0 ml

http://www.nature.com/mtna/journal/v3/n8/extref/mtna201441x3.ppt

Date added: November 21, 2014 - Views: 1

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He, et al., Chemical Science, 2011 Raman shift (cm-1) Assignments Aptamer (*) 1316 Adenine (ring stretching) 1022 DNA backbone(PO2- stretching) 792 thymine, ...

http://blog.lib.umn.edu/chaynes/8152/Lecture21_clh_class.ppt

Date added: November 25, 2011 - Views: 13

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15 Slides.ppt - Test Page for Apache Installation

… an ‘expression platform’ for gene regulation. A metabolite-binding ‘aptamer’ domain and … Riboswitch Functions U U U U U X 3 4 2 1 Direct (protein-free ...

http://ender.bu.edu/~tgardner/be209/lectures/15/15%20Slides.ppt

Date added: February 2, 2012 - Views: 20

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Introduction Basic processes Features 2. Methods 3. Aptamer base 1. SELEX (systematic evolution of ligands by exponential enrichment) is a process that ...

http://www.biopharmagen.com/SELEX%20by%20%20%e8%a4%9a%e7%95%85.ppt

Date added: November 21, 2014 - Views: 1

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Aptamer antagonist of tissue factor pathway inhibitor. Improved thrombin generation in plasma from subjects with FVIII deficiency. Improved clot times as measured by ...

http://www.ohsu.edu/xd/health/services/cancer/getting-treatment/why-ohsu/for-healthcare-professionals/continuing-ed/upload/Recht_12-01-21-bleeding-2012.pptx

Date added: April 19, 2013 - Views: 19

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DNA . ppt - Biology Resources

The DNA of the nucleus makes a single strand of messenger RNA (ribo-nucleic acid) which leaves the nucleus and builds up the protein in the cytoplasm.

http://www.biology-resources.com/powerpoints/Genetics/01-DNA/DNA.ppt

Date added: December 17, 2011 - Views: 247

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Slide 1

Reserve your “block” now We have developed a proprietary, high-throughput process for DNA aptamer production. Supply any protein target, and receive a custom ...

http://www.iceninebio.com/aptamer/aptamer-services.ppt

Date added: February 17, 2014 - Views: 1

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Duke Clinical Research Institute - dukecardiologyfellows

Monoclonal Antibody Aptamer Aptamer Aptamer Antidote Aptamer Aptamer-antidote Pairs Aptamers Encode their Own Antidotes DCRI/ Regado Biosciences Anti -FIXa Aptamer ...

http://www.dukecardiologyfellows.org/dcfblog/wp-content/uploads/translational-science-20121.ppt

Date added: May 5, 2013 - Views: 13

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REG1: Pegnivacogin + AnivamersenRegado Biosciences, Inc. Novel Anticoagulation System. RNA aptamer . Factor IXa inhibitor. Controlling agent. Active. Specific

http://clinicaltrialresults.org/Slides/RADAR%20ACC11%20LBCT%20040311%20final_Povsic.ppt

Date added: November 10, 2011 - Views: 11

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Slide 1

Aptamer vs, prostate cancer cell membrane antigen (PMSA), conjugated to rhodamine Potential use as an anticancer diagnostic, and therapeutic.

http://www.cs.duke.edu/~reif/temp/aptamers/evolving%20aptamers/overview%20slides%20of%20SELEX/aptamers04.ppt

Date added: May 5, 2013 - Views: 40

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Inquiry into Life Twelfth Edition

Lecture PowerPoint to accompany Molecular Biology Fourth Edition Robert F. Weaver Chapter 7 Operons: Fine Control of Bacterial Transcription Copyright © The McGraw ...

http://highered.mheducation.com/sites/dl/free/0072995246/444682/chapt07_lecture.ppt

Date added: August 9, 2014 - Views: 1

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Bottom picture: four high school students and one REU student received the training of synthesizing aptamer-based nanostructured alginate hydrogels for drug release.

http://www.nsf.gov/mps/dmr/highlights/10highlights/highlights2010/0705716_Wang.ppt

Date added: November 21, 2014 - Views: 1

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Folie 1 - FLI - Leibniz

The Aptamer Database is a comprehensive, annotated repository for information about aptamers and in vitro selection. This resource is provided to collect, ...

http://www.fli-leibniz.de/www_bioc/3D/3D_LECTURE_2007_2.ppt

Date added: September 30, 2012 - Views: 5

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S-aptamer-tagged ARE and mtARE reporters were used for in vivo Crosslinking-coupled RNP purificaiton followed by RPA assay High-mobility group A2 (HMGA2) ...

http://www.microbio.uab.edu/ptrm/2008/ChaoLi/li92308.ppt

Date added: June 1, 2013 - Views: 5

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... Intracellular Lung Tarceva, Iressa Aptamer Cell Surface, Intracellular Renal, Lung AS1411 (in dev.) Peptide Cell Surface, Intracellular Breast, Thyroid RGD ...

http://unithertechnologyconference.com/downloads09/SessionsDayOne/BURGESS_web.ppt

Date added: November 11, 2011 - Views: 30

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UK lecture - University of California, Irvine

... Another RNA aptamer example: adenosine aptamer Class II ligase ribozyme Pitt & Ferré-D’Amaré, J. Am. Chem. Soc., 2009, 131 (10), ...

http://www.chem.uci.edu/~aluptak/110715_UK_Lecture.ppt

Date added: December 10, 2013 - Views: 2

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... aptamer: target. Soontornworajit B, Zhou J, Shaw MT, Fan, TS, Wang Y. Chemical Communications 2010; 46:1857-1859. Nucleic Acid Aptamers . Single-stranded ...

http://omicsonline.org/editor-ppt/Yong_Wang.pptx

Date added: November 3, 2014 - Views: 1

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... First Anti Angiogenic Agent 28 Base RNA Aptamer NON-IMMUNOGENIC NATURE Selectively binds extra cellular VEGF 165 DOES NOT EFFECT NORMAL VASCUALR GROWTH ...

http://www.jdosmp.org/pps/antiVEGF_rs.ppt

Date added: June 2, 2013 - Views: 32

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No Slide Title

... 313, 1752-6 regulatory elements which control a wide set of metabolic pathways in bacteria consist solely of RNA Aptamer domain: ...

http://www.microbio.uab.edu/ptrm/neiderwies/niederweis.ppt

Date added: December 14, 2011 - Views: 27

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... Intracellular Peptide AS1411 (in dev.) Cell Surface, Intracellular Aptamer Her2, Erbitux Cell Surface Monoclonal Antibody Functionality Dispersion ...

http://unithertechnologyconference.com/downloads/SESSION%205/Burgess_NEW.ppt

Date added: November 5, 2011 - Views: 25

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Aptamers as potential therapeutic molecules

Characterization of antithrombin-specific RNA aptamers for use in anticoagulant therapy Yolanda M. Fortenberry, Ph.D. Hematology 2014 Conference

http://omicsgroup.com/conferences/ACS/conference/speaker_ppt/14612-Speaker-ppt.ppt

Date added: November 21, 2014 - Views: 1

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Ribozyme course - ETH Zurich: Welcome to the Institute of ...

... Selection of new ribozymes (RNA world) The ATP aptamer structure Nucleolin RNA Targets B1 10-50nM (5’ETS) Mouse B2 50-100nM (5’ETS) ...

http://www.mol.biol.ethz.ch/groups/allain_group/teaching/Ribozyme-course.ppt

Date added: October 7, 2011 - Views: 48

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No Slide Title

Terminator Aptamer Research focus on riboswitches Bioinformatics Without TPP What are Riboswitches? Anti-terminator Aptamer Vitamin B1 biosynthesis in bacteria: ...

http://in.bgu.ac.il/fohs/Documents/Presentations/dbarash_riboswitch_presentation_2013.ppt

Date added: July 30, 2013 - Views: 5

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Extensive and global regulation of transcription Shifts in

The aptamer is called the RFN ... 2 Slide 3 REGULON Extensive and global regulation of transcription in prokaryotes Slide 6 Endospore formation Slide 8 ...

http://www.sbs.utexas.edu/herrin/bio344/lectures/L11_proktransc4_Organ1.ppt

Date added: April 12, 2012 - Views: 19

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Inquiry into Life Twelfth Edition - 株式会社 化学同人

... Activation of mRNA Translation When TPP abundant Binds aptamer Causes conformational shift in mRNA Ties up Shine-Dalgarno in 2° structure Shift hides the SD ...

http://www.kagakudojin.co.jp/weaver/ppt_lecture/chapt17_lecture.ppt

Date added: February 5, 2012 - Views: 5

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Indicator Displacement Assays for Solute Sensing

Indicator Displacement Assays for Solute Sensing Julee Byram Mecozzi Group May 10, 2007 * * * * * * * * * * * * * * * * * * * * * * * * * Aptamer-Based Sensor for ...

http://www.chem.wisc.edu/areas/organic/studsemin/byram/byram-sem.ppt

Date added: November 2, 2011 - Views: 19

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NCI Alliance for Nanotechnology in Cancer: Research Advances ...

... ErbB3 Targeted Aptamer-Nanoparticle Conjugate, Massachusetts General Hospital, Boston, Mass. Carolina Center of Cancer Nanotechnology Excellence, ...

http://deainfo.nci.nih.gov/advisory/bsa/bsa0608/presentations/monday/1001%20Rosen.ppt

Date added: June 26, 2012 - Views: 40

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aptamer. fragments. Anal Method . 2011; 3:59-61. ... Lead: 100 ppt (2 orders of magnitude below the EPA standard limit) 2-3 orders of magnitude. Small molecules. 7 nM

http://nanodiscoveryinc.com/yahoo_site_admin/assets/docs/NanoDLSay.50102502.pptx

Date added: June 10, 2013 - Views: 15

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Slide 1

... (Vienna RNA) Aptamer/Antiterminator/Terminator competition Evidence for natural selection of reliably folding sequences Probability of no selection P ~ 0.01 ...

http://www.math.rutgers.edu/events/smm/michael.widom.ppt

Date added: May 11, 2013 - Views: 10

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No Slide Title

Research focus on riboswitches Bioinformatics Searching for riboswitches in eukaryotes by their aptamer Sequence is not enough, need structure considerations!

http://in.bgu.ac.il/fohs/Documents/Presentations/dbarash_riboswitch_presentation_brief_2013.ppt

Date added: August 31, 2013 - Views: 1

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... Multiple Isoforms of VEGF-A Are Generated from Exon Splicing VEGF Inhibition in AMD FDA approved Pegaptanib Aptamer Specific for VEGF-A isoform 1651 ...

http://www.projectsinknowledge.com/Init/MC/1772/1772-Slides.ppt

Date added: October 16, 2011 - Views: 85

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Applications of Spectrophotometry - Schreiner University

Applications of Spectrophotometry Ch. 19 Analysis of a Mixture The absorbance of a solution at any wavelength is the sum of the absorbances of all species in the ...

http://faculty.schreiner.edu/bholloway/S%202006%20CHEM%203402%20Applications%20of%20Spectrophotometry-Sean%20Collins.ppt

Date added: April 23, 2012 - Views: 35

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Slide 1

Class 27_11 last updated 12/14/11 12:30 PM Limitations of siRNA silencing in mammalian cells Transient nature of the response (~3 days) Transfection problems (cell ...

http://www.columbia.edu/cu/biology/courses/w3034/Larry/class27_11.ppt

Date added: January 27, 2012 - Views: 17

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Anticoagulation: Past, Present and Future

Title: Anticoagulation: Past, Present and Future Author: n693173 Last modified by: Cathy Cheng Created Date: 9/27/2012 1:52:43 PM Document presentation format

http://www.fpm.emory.edu/Family/didactics/powerpint/Anticoagulation_current_and_future_therapies.ppt

Date added: May 2, 2013 - Views: 23

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CU Boulder Research, Scholarly Activity, and Creative Works GSAC April 30, 2010 Russ Moore, Interim VC Research Research & Scholarly Works Remarkable record of ...

http://www.colorado.edu/graduateschool/aboutus/gsac/minutes/april10/GSAC(S10)RMpresentation.ppt

Date added: August 1, 2013 - Views: 295

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PSMA aptamer–Smg1 siRNA rejection of PSMA-expressing, but not parental, CT26 tumour cells. F Pastor et al. Nature 465, 227-230 (2010) doi:10.1038/nature08999

http://www.nature.com/nature/journal/v465/n7295/slides/nature08999-pf3.ppt

Date added: November 21, 2014 - Views: 1

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RFID Biosensors for the Detection of IEDs at 400 m Stand-off ...

Presently involved in aptamer, peptide, antibody and plasma-deposited hydrogels research. Currently developing an RFID/Biosensor. Technology Background (3) ...

http://zensensing.com/media/powerpoint/Hunt-and-Edmonson-DARPA-Presentation-Nov-16-2005.ppt

Date added: May 2, 2013 - Views: 4

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Diapositiva 1 - UB

Study of the interaction between the porphyrin TmPyP4 and the Thrombin Binding Aptamer (TBA) G-quadruplex ... guanine3 guanine4 pKa = 10,5 0,1 TmPyP4 Melting

http://www.ub.edu/gesq/dna/presentations/tba_tmpyp4.ppt

Date added: March 7, 2012 - Views: 19

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Riboswitches - Weizmann Institute of Science

... Aptamer domain (responsible for binding of ligand) Expression plataform (responsible for impacting gene expression) Structure Mechanism Three known ...

http://www.weizmann.ac.il/plants/aharoni/FrontiersCourse/Sharon-Riboswitches3.ppt

Date added: May 11, 2013 - Views: 23

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Folie 1 - FLI - Leibniz

- 2013/2014 - 3D Structures of Biological Macromolecules Part 3: Nucleic Acids Jürgen Sühnel [email protected] Leibniz Institute for Age Research, Fritz ...

http://www.fli-leibniz.de/www_bioc/3D/3D_LECTURE_2013_3.ppt

Date added: April 19, 2014 - Views: 6