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Solubilization of Particulate Proteins and Nonelectrolytes by ...

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Solubilization of Particulate Proteins and Nonelectrolytes by ...

solubilization of particulate proteins and nonelectrolytes by chaotropic agents* by y. hatefi and w. g. hanstein department of biochemistry, scripps clinic and research foundation,

http://www.jstor.org/stable/59368

Date added: May 25, 2013 - Views: 29

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Hydrotropic solubilization of poorly watersoluble drugs

tion and solubilization capacity of hydrotropes can obtained from the effect of hydrotrope concentration. We measured the solubilization of several poorly ... The aqueous solubility of organic nonelectrolytes is given by the following expression:

http://www.kinam.com/Articles/PMicelles%20Papers/Kim,%20J.%2010%20J%20Pharm%20Sci.pdf

Date added: April 25, 2012 - Views: 30

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Solubility of gases in liquids: a critical review

Solubility of gases in liquids: a critical review Emmerich Wilhelm ... (solubilization) (47). ... relatively simple aqueous solutions of nonelectrolytes (with special attention to hydrophobic effects). In a loose way, ...

http://pac.iupac.org/publications/pac/pdf/1985/pdf/5702x0303.pdf

Date added: December 14, 2012 - Views: 11

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Experimental and Computational Methods Pertaining to Drug ...

I is predominant whereas for nonelectrolytes S M is the Solvent molecules Solute molecules Solution www.intechopen.com. ... solubility of drug, is the solubilization power of the cosolvent and theoretically is equal to (log(/ )) ...

http://cdn.intechopen.com/pdfs/28120/InTech-Experimental_and_computational_methods_pertaining_to_drug_solubility.pdf

Date added: October 1, 2012 - Views: 3

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Aqueous and Cosolvent Solubility Data for Drug-like Organic ...

aqueous solubility model, a set of 321 structurally diverse drugs was collected from literature for the analysis. For the ... based on its good solubilization properties and overall acceptability in terms of side-effect profile.2

http://link.springer.com/content/pdf/10.1208%2Faapsj070110.pdf

Date added: September 9, 2013 - Views: 1

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SOLUTIONS - Pennsylvania State University

partially ionized in solution poor conductors Nonelectrolytes not ionized in solution non-conductors. ... the given conditions solubility Supersaturated solution: more than the max conc of solute ... equals rate of solubilization ...

http://courses.chem.psu.edu/chem110/faculty/asbury/Lec28-30_web.pdf

Date added: February 5, 2012 - Views: 5

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ASSOCIATE EDITOR: ARTHUR CHRISTOPOULOS Strategies to Address ...

Reduced Particle Size and Enhanced Drug Wetting and Solubilization .....419 2. ... For nonelectrolytes, solubility behavior is not complicated by the effects of ionization and remains a function of hydration and the strength of the crystal lattice.

http://pharmrev.aspetjournals.org/content/65/1/315.full.pdf

Date added: February 14, 2014 - Views: 2

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Experimental and Computational Methods Pertaining to Drug ...

For strong electrolytes, SI is predominant whereas for nonelectrolytes S M is the Solvent molecules Solute molecules Solution www.intechopen.com. ... solubility of drug, V is the solubilization power of the cosolvent and theoretically is equal to (lo g ...

http://cdn.intechopen.com/pdfs-wm/28120.pdf

Date added: June 6, 2014 - Views: 1

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CHAPTER -I INTRODUCTION - INFLIBNET

As is usually the case for nonelectrolytes in water, there will be less than complete ... In order to gain as insight into the probable mechanism of solubilization; solubility, spectral, solution properties, gel formation, paste formation, ...

http://shodhganga.inflibnet.ac.in/jspui/bitstream/10603/6439/7/07_chapter%201.pdf

Date added: December 10, 2013 - Views: 1

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ESTIMATION OF ETHANOL /WATER SOLUBILITY PROFILES by Stephen ...

nonelectrolytes by Martin (1979) and Yalkowsky (1979). Applying this approximation to equation 1.4; log X ideal . ... Yalkowsky S. H., 1999, Solubility and Solubilization in Aqeuous Media, Oxford University Press, New York. Yalkowsky, S.H.; Roseman, T.J., 1981, ...

http://arizona.openrepository.com/arizona/bitstream/10150/193915/1/azu_etd_1659_sip1_m.pdf

Date added: May 20, 2013 - Views: 2

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M. Pharm. (Pharmaceutics) COURSE STRUCTURE AND SYLLABUS I ...

1 M. Pharm. (Pharmaceutics) COURSE STRUCTURE AND SYLLABUS I YEAR I SEMESTER Code Group Subject L P Credits Modern Pharmaceutical Analytical

http://www.pharmainfo.net/files/syllabusandqainfo/jntu_hyderabad_m.pharm_pharmaceutics_1st_sem_syllabus.pdf

Date added: July 11, 2013 - Views: 14

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Dear Patrons & Well Wishers Contents - BS Publication- S

Solubility and Solubilization of Nonelectrolytes 2. Drug Solubilization in Surfactant Systems 3. Solubilization of Drugs by cosolvents 4. Alteration of Apparent Solubility through Complexation 5. Solubilization by Solid-State Manipulation 6.

http://www.bspublications.net/downloads/04ee5d014c46f5_PMP%20catalogue-Jan-2012.pdf

Date added: September 19, 2012 - Views: 13

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TU 293 Binding can increase the mobility and uptake of ...

... posing technical challenges for producing reliable kinetic data because of low PAH solubilities and sorptive losses . To overcome these, an experimental approach based on dynamic passive dosing is presented which: ...

http://orbit.dtu.dk/fedora/objects/orbit:112693/datastreams/file_9708394/content

Date added: December 10, 2013 - Views: 1

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Interaction of small* molecules with membranes.

... Membrane permeability to nonelectrolytes 4) Water permeability 5) Membrane potential at the surface ... ¾detergents - insertion, solubilization, ... Solubility-diffusion model: (assumption: ...

http://www.mpikg.mpg.de/th/people/dimova/courses/handouts/l4handouts.pdf

Date added: May 26, 2013 - Views: 4

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FACULTY OF PHARMACY ϵϥناعنا Ϧادϯسنا عماج

osmotic pressure of nonelectrolytes –van’t Hoff and morse equations for osmotic pressure – osmotic ... (micelle formation and solubilization ,antibacterial activity , foam formation and antifoaming agent . wetting effect ,emulsifying agent and detergents).

http://www.siu-sd.com/library/curriculum/ph/PHARMA_Semester%203.pdf

Date added: August 3, 2013 - Views: 1

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Study of the Cloud Point of C12EO6 and C12EO8 Nonionic ...

lytes as well as nonelectrolytes have a large effect on the cloud point (CP) of C12EO6 and C12EO8 nonionic surfactants, because of their effect on water structure and their hydrophilicity. The presence of NaI and KI in the systems leads to a substantial in-

http://www.hanser-elibrary.com/doi/pdf/10.3139/113.110199

Date added: September 24, 2014 - Views: 1

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A Method for Determining the 1-Octanol/Water Partition ...

Stable and hydrophobic nonelectrolytes are generally more or less volatile. The new ... solubilization effect on a volatile solute, ... 1. S. H. Yalkowsky and S. Banerjee, "Aqueous Solubility, Methods of Estimation for Organic Compounds", Marcel Dekker, New York, 1992. 2. A ...

http://pdf.lookchem.com/pdf/22/afbad729-f297-4977-b9e4-1cb291fe4c5e.pdf

Date added: May 26, 2013 - Views: 2

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CV updated 05 30 031-1 - University of Wisconsin–Madison

3 29. “Solubility of Nonelectrolytes in Polar Solvents, III” (with S.H. Yalkowsky, G.L. Amidon, and G.L. Flynn), J. Pharm. Sci., 65, 48 (1975).

http://apps.pharmacy.wisc.edu/facstaff/sciences/Zografi.pdf

Date added: January 11, 2013 - Views: 4

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Ananda Vardhan Hebbani and John

like proteins and nucleic acids by increasing the solubility of non-polar solute particles in aqueous medium. As the chaotropic agents are less polar than water, ... because the solubilization of lipids by chaotropes, relative to that by detergents, is selective (Oku and MacDonald,

http://bretj.com/journals/download_paper/183

Date added: October 25, 2014 - Views: 1

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Study of Charged Particles Transport across Model and Real ...

rate of diffusion of organic molecules – nonelectrolytes ... The higher is the molecular solubility in fats, the faster is the diffusion rate across the membrane. ... for their solubilization). Those thoroughly studied [3]

http://www.wseas.us/e-library/conferences/2009/tenerife/EED/EED-36.pdf

Date added: May 26, 2013 - Views: 2

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Study of Charged Particles Transport across Model and Real ...

rate of diffusion of organic molecules – nonelectrolytes ... The higher is the molecular solubility in fats, the faster is the diffusion rate across the membrane. ... for their solubilization). Those thoroughly studied [17]

http://www.wseas.us/e-library/transactions/environment/2010/89-307.pdf

Date added: January 26, 2013 - Views: 2

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Parámetro de Solubilidad Requerimiento Dieléctrico Nipasol ...

tivity experimental data and from empiric solubilities of the solutes in the whole ... ques of solubilization of Drugs". Marcel Dek- ker, United ... 463-4 5. Hildebrand, J.H. & R.L. Scott (1949) "7be Solu- bility of Nonelectrolytes" 3rd Ed., Reinhold Pu- blisliing Corp., N.Y do de ...

http://www.latamjpharm.org/trabajos/19/1/LAJOP_19_1_1_9_H531T5ZG1Y.pdf

Date added: March 20, 2013 - Views: 2

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Chapter 6 Solubility and Partition Phenomena

Solubility of Gases in Liquids IV. Solubility of Liquids in Liquids V. Solubility of Solids in Liquids VI. Partition Phenomena. ⅠGeneral Principles 1. ... soluble in water Nonelectrolytes: high-molecular-weight organic drugs that do not dissociate or

http://pharm.skku.edu/erp/erpmenus/lesson_pds/uploadfiles/%EC%9A%A9%ED%95%B4%EB%8F%84%EB%B6%84%EB%B0%B0.pdf

Date added: May 17, 2013 - Views: 2